Patent · US Active

Benzimidazole derivatives and uses thereof

US10040767B2 · kind B2 · utility

0Cited by
5References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 14, 2015
Grant dateAug 7, 2018
Priority date
Expiry dateMay 14, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Benzimidazole derivatives of Formula I, that modulate the activity of ACSS2 are disclosed for therapeutic use. The fused imidazole ring of the compounds disclosed has a diarylmethyl or diarylmethanol moiety attached at the 2-position and the as compounds have at least one other substituent at the 5 or 6 position of the benzimidazole. Also disclosed are methods of using the benzimidazole compounds for the treatment of diseases or disorders, such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.