Synthesis of chirally enriched 2,4-disubstituted tetrahydropyran-4-ol and its derivatives
US10040775B2 · kind B2 · utility
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Key dates
| Filing date | Oct 16, 2015 |
| Grant date | Aug 7, 2018 |
| Priority date | — |
| Expiry date | Oct 16, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC11D7/267
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a process for synthesis of chiral 2,4-disubstituted-tetrahydropyran-4-ol and its derivatives having a general formula (I) comprising of asymmetric reaction of an aliphatic aldehyde and a homoallylic alcohol in the presence of a chiral organocatalyst, and a fragrance and cosmetic composition containing chirally enriched molecules of the said general formula (I) prepared by the aforesaid process.
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