Patent · US Active

Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto

US10040783B2 · kind B2 · utility

1Cited by
1References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 30, 2016
Grant dateAug 7, 2018
Priority date
Expiry dateNov 30, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D403/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, neuroinflammation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.