Selective photoactivation of amino acids for single step peptide coupling
US10040818B2 · kind B2 · utility
12Cited by
1References
8Claims
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Key dates
| Filing date | Feb 23, 2015 |
| Grant date | Aug 7, 2018 |
| Priority date | — |
| Expiry date | Feb 23, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are formulations, substrates, and arrays for amino acid and peptide synthesis on microarrays. In certain embodiments, methods for manufacturing and using the formulations, substrates, and arrays including one-step coupling, e.g., for synthesis of peptides in a C→N orientation are disclosed. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.