Patent · US Active

Chemically modifying peptides

US10040819B2 · kind B2 · utility

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26Claims

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Assignee

UNIVERSITY OF DURHAM · GB

Inventors

Steven Cobb · Tulsa, US
Christopher Coxon · Durham, GB
Graham Sandford · Durham, GB

Key dates

Filing date	May 28, 2015
Grant date	Aug 7, 2018
Priority date	—
Expiry date	May 28, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K1/113
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.