CRHR2 peptide agonists and uses thereof
US10040838B2 · kind B2 · utility
0Cited by
12References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 4, 2009 |
| Grant date | Aug 7, 2018 |
| Priority date | — |
| Expiry date | Aug 8, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel peptides that are selective corticotrophin releasing hormone receptor type 2 (CRHR2) agonists and compositions thereof for the treatment, amelioration or inhibition of cardiovascular conditions, including but not limited to heart failure. The novel peptide agonist preferably comprise modifications that include pegylated peptides. Furthermore, the present invention also relates to methods for the treatment and prevention of a disease or disorder related to CRHR2 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.