Caninized anti-nerve growth factor antibodies
US10040849B2 · kind B2 · utility
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Key dates
| Filing date | May 8, 2012 |
| Grant date | Aug 7, 2018 |
| Priority date | — |
| Expiry date | Jul 9, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/734
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of preparing an antibody suitable for use in a canine is provided. Also provided are caninized antibodies which specifically bind to canine neuronal growth factor (NGF) and neutralize the ability of canine NGF to bind to the p75 or TrkA canine NGF receptor. The invention extends to nucleic acids encoding same and to methods of treating pain and arthritis in a canine using said antibodies and/or nucleic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.