Method of producing erythrocytes without feeder cells
US10041043B2 · kind B2 · utility
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Key dates
| Filing date | Dec 22, 2015 |
| Grant date | Aug 7, 2018 |
| Priority date | — |
| Expiry date | Dec 22, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are methods of producing erythrocytes from hematopoietic cells, particularly hematopoietic cells from placental perforate in combination with hematopoietic cells from umbilical cord blood, wherein the method results in accelerated expansion and differentiation of the hematopoietic cells to more efficiently produce administrate erythrocytes. Further provided herein is a bioreactor in which hematopoietic cell expansion and differentiation takes place.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.