Patent · US Active

System and method for time-resolved fluorescence imaging and pulse shaping

US10041883B2 · kind B2 · utility

10Cited by

4References

12Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Warren S. Grundfest · Los Angeles, US
Oscar M. Stafsudd · Los Angeles, US
Pei-Chi Jiang · Los Angeles, US
Asael Papour · Los Angeles, US
Zachary Taylor · Los Angeles, US
Maie A. St. John · Los Angeles, US

Key dates

Filing date	Aug 29, 2014
Grant date	Aug 7, 2018
Priority date	—
Expiry date	Jun 5, 2036

Classification

Technology area (CPC G)Physics
CPC primaryG01N2201/0621
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A time-resolved fluorescence imaging (TRFI) system that images a target medium without lifetime fitting. Instead of extracting the lifetime precisely, the system images the fluorophore distribution to allow for a simple and accurate method to obtain the fluorescence image without lifetime-extraction for time-resolved fluorescence imaging. An illumination source circuit for TRFI is also disclosed that shapes the excitation pulse. In one embodiment, the illumination source comprises an LED and stub line configured for generating a linear decay profile.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.