Pharmaceutical composition containing clomipramine and preparation method therefor
US10045944B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 29, 2014 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Dec 29, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1611
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a pharmaceutical formulation comprising clomipramine or its pharmaceutically acceptable salt (preferably, clomipramine hydrochloride) as the first active ingredient, and sildenafil or its pharmaceutically acceptable salt (preferably, sildenafil citrate) as the second active ingredient, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation. In particular, the present invention provides a pharmaceutical formulation comprising the above two active ingredients and manufactured by using a wet granulation method, wherein stability of clomipramine is improved, and a method for manufacturing this pharmaceutical formulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.