Nucleic acid-encapsulating polymer micelle complex and method for producing same
US10046065B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Aug 5, 2014 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Aug 5, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nucleic acid-encapsulating polymer micelle complex is formed of a block copolymer containing an uncharged hydrophilic polymer chain block and a cationic polymer chain block; and two single-stranded DNA molecules having mutually complementary base sequences of 1000 or more bases in length, double-stranded DNA of 1000 or more base pairs in length in which at least a part of a double helix structure is dissociated and forms a single-stranded structure, or one single-stranded DNA molecule of 1000 or more bases in length.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.