Efficient process of asymmetric hydrogenation of unsaturated ketones using additives
US10047019B2 · kind B2 · utility
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Key dates
| Filing date | Dec 18, 2013 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Dec 18, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process of the asymmetric hydrogenation of an unsaturated ketone or aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex and in the presence of at least one additive and a halogenated alcohol. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.