Patent · US Active

Modified alpha hemolysin polypeptides and methods of use

US10047129B2 · kind B2 · utility

1Cited by

7References

16Claims

0Family size

Assignee

ELECTRONIC BIOSCIENCES, INC. · US

Inventors

Geoffrey Barrall · San Diego, US
Eric N. Ervin · Holladay, US
Prithwish Pal · San Diego, US

Key dates

Filing date	Dec 19, 2013
Grant date	Aug 14, 2018
Priority date	—
Expiry date	Jan 6, 2034

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/143333
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided herein are alpha hemolysin polypeptides comprising modified amino acid sequences that can reduce the rate of translocation of a polymer. Also provided herein are apparatuses and devices comprising modified hemolysin polypeptides. Also provided herein are methods of using modified alpha hemolysin proteins for use in characterizing and/or sequencing a polymer or for use as molecular sensors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.