Multispecific constructs
US10047163B2 · kind B2 · utility
2Cited by
4References
3Claims
0Family size
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Key dates
| Filing date | Feb 7, 2014 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Apr 30, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are novel multispecific antibody constructs and multispecific antibody drug conjugates (ADCs), and methods of using such antibodies and ADCs to treat cancer. IgG-like bispecific antibodies have different binding specificities on each arm of the antibody. They are similar in structure to monospecific IgGs in that they contain two heavy chains with VH, CH1, CH2 and CH3 regions, and two light chains with VL and CL regions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.