Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
US10047340B2 · kind B2 · utility
2Cited by
20References
18Claims
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Key dates
| Filing date | Dec 20, 2012 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Dec 20, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2517/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for producing stem cell banks, preferably human, which optionally may be transgenic, e.g., comprised of homozygous MHC allele cell lines are provided. These cells are produced preferably from parthenogenic, IVF, or same-species or cross-species nuclear transfer embryos or by dedifferentiation of somatic cells by cytoplasm transfer. Methods for using these stem cell banks for producing stem and differentiated cells for therapy, especially acute therapies, and for screening for drugs for disease treatment are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.