Generation of keratinocytes from pluripotent stem cells and maintenance of keratinocyte cultures
US10047341B2 · kind B2 · utility
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31Claims
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Key dates
| Filing date | Oct 13, 2015 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Oct 13, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods for the generation of functional keratinocyte stem cells that are differentiated directly from human ESCs/iPSCs in a chemically defined serum-free cell culture system, as well as cells derived therefrom and methods of use thereof. Also provided are methods for culturing primary keratinocytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.