Patent · US Active

Disulfide-containing alkyne linking agents

US10047361B2 · kind B2 · utility

0Cited by

4References

12Claims

0Family size

Assignee

Arrowhead Pharmaceuticals, Inc. · US

Inventors

Aaron Almeida · Madison, US
Andrei V. Blokhin · Fitchburg, US
Darren H. Wakefield · Fitchburg, US
Jonathan D. Benson · Stoughton, US
David B. Rozema · Madison, US

Key dates

Filing date	Sep 27, 2017
Grant date	Aug 14, 2018
Priority date	—
Expiry date	Sep 27, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/50
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described are improved disulfide-containing alkyne linking agents having have branched disulfides. The improved linking agents exhibit improved stability. The linking agents are useful for attachment of oligonucleotides to targeting groups or delivery agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.