Method for the diagnosis, prognosis and treatment of breast cancer metastasis
US10047398B2 · kind B2 · utility
14Cited by
8References
13Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 5, 2011 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Feb 17, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the diagnosis or the prognosis of metastasis in breast cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in ER− breast cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the ER− breast cancer metastasis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.