Laplacian and Tikhonov regularization for voltage mapping with a medical device
US10049771B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 15, 2013 |
| Grant date | Aug 14, 2018 |
| Priority date | — |
| Expiry date | Jan 20, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/318
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An embodiment of a method for solving the inverse problem of electrophysiology and determining a voltage distribution on a surface of a tissue may comprise receiving a plurality of voltages collected by a plurality of electrodes adjacent to the surface, discretizing the problem using a Finite Element Method (FEM) or a Boundary Element Method (BEM), introducing one or more regularization terms to an error minimization formulation, and solving, by a processor, the voltage distribution according to the plurality of voltages and according to the regularization terms. The regularization terms may comprise one or more of a Laplacian smoothness operator, a Tikhonov regularization matrix, a confidence matrix, and a linear operator that interpolates the plurality of electrode voltages to the tissue voltage distribution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.