Determining functional severity of stenosis

US10052031B2 · kind B2 · utility

Assignee

• Siemens Healthcare Limited · DE

Inventors

• Puneet Sharma · Rahway, US
• Ali Kamen · Skillman, US
• Max Schöbinger · Hirschaid, DE
• Michael Scheuering · Koblenzer Straße, DE
• Dorin Comaniciu · Princeton Junction, US

Key dates

• Filing date: Feb 14, 2014
• Grant date: Aug 21, 2018
• Expiry date: Oct 11, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30101
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method for determining functional severity of a stenosis includes: (a) generating a simulated perfusion map from a calculated blood flow; (b) comparing the simulated perfusion map to a measured perfusion map to identify a degree of mismatch therebetween, the measured perfusion map representing perfusion in a patient; (c) modifying a parameter in a model used in calculating the blood flow when the degree of mismatch meets or exceeds a predefined threshold; (d) computing a hemodynamic quantity from the simulated perfusion map when the degree of mismatch is less than the predefined threshold, the hemodynamic quantity being indicative of the functional severity of the stenosis; and (e) displaying the hemodynamic quantity. Systems for determining functional severity of a stenosis are described.