Patent · US Active

Use of ivermectin and derivatives thereof

US10052340B2 · kind B2 · utility

0Cited by

2References

3Claims

0Family size

Assignee

XIAMEN UNIVERSITY · CN

Inventors

Yong Li · Corvallis, US
Lihua JIN · Xi'an, CN
Xuhui FENG · Xiamen, CN

Key dates

Filing date	Jun 24, 2013
Grant date	Aug 21, 2018
Priority date	—
Expiry date	Jul 29, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the new use of antiparasitic agents, such as ivermectin, abamectin/avermectin, doramectin and so on, and the design method of the derivatives for the new use. The said compounds including macrolide abamectin/avermectin, ivermectin, doramectin and the derivatives thereof, may be used in the manufacture of a medicament for use in treating metabolic related diseases in a mammal, such as hyperglycemia, insulin resistance, hypertriglyceridemia, hypercholesterolemia, diabetes, obesity, etc, and Famesoid X receptor mediated diseases, such as cholestasia, gallstone, non alcohol fatty liver disease, atherosclerosis, inflammation, cancer, etc.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.