Patent · US Active

Mesenchymal stem cells for the treatment of CNS diseases

US10052363B2 · kind B2 · utility

1Cited by

14References

7Claims

0Family size

Assignees

Ramot at Tel-Aviv University Ltd. · IL
BRAINSTORM CELL THERAPEUTICS LTD. · IL

Inventors

Avinoam Kadouri · Netanya, IL
Avihay Bar-Ilan · Nes Ziona, IL
Eldad Melamed · Nes Ziona, IL
Daniel Offen · Gdera, IL
Ofer Sadan · Nes Ziona, IL
Merav Bahat-Stromza · Haifa, IL

Key dates

Filing date	Sep 11, 2016
Grant date	Aug 21, 2018
Priority date	—
Expiry date	Oct 1, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2506/1353
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.