Pharmaceutical compositions comprising CpG oligonucleotides
US10052378B2 · kind B2 · utility
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Key dates
| Filing date | Jun 12, 2015 |
| Grant date | Aug 21, 2018 |
| Priority date | — |
| Expiry date | Jun 12, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2730/10134
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a pharmaceutical composition for inducing immune response in a subject, comprising: (a) an antigen with a concentration ranging from 1 μg/ml to 100 μg/ml; (b) CpG oligonucleotides having a sequence of 5′-tcgacgttcgtcgttcgtcgttc-3′, with a concentration ranging from 25 μg/ml to 500 μg/ml, and (c) an aluminum adjuvant with a concentration ranging from 25 μg/ml to 500 μg/ml. Such pharmaceutical composition can induce or boost immune response against antigen in the subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.