Multifunctional nanomaterials for the treatment of cancer

US10052393B2 · kind B2 · utility

Assignee

• The Regents of the University of Colorado, a Body Corporate · US

Inventors

• Wounjhang Park · Superior, US
• Thomas Flaig · Radolfzell, DE
• Xiaoping Yang · Streetsboro, US
• Lih-Jen Shih Su · Denver, US
• Kazunori Emoto · Broomfield, US

Key dates

• Filing date: Jan 25, 2013
• Grant date: Aug 21, 2018
• Expiry date: Mar 6, 2035

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B82Y5/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a multifunctional nanomaterial comprising a nanorod comprising 1) a noble metal, wherein the nanorod exhibits surface plasmon resonance absorption in the near-infrared spectrum; 2) an up-conversion phosphor that absorbs infrared light and emits visible luminescence; and optionally 3) a biomolecule targeting moiety. The invention further relates to methods of detecting and treating cancer using the multifunctional nanomaterials of the invention.