Pyrrolopyrimidine derivatives as TAM inhibitors

US10053465B2 · kind B2 · utility

Assignee

• Incyte Corporation · US

Inventors

• Yun-Long Li · Chadds Ford, US
• David M. Burns · Woodbury, US
• Hao Feng · Chester, US
• Joseph Glenn · Sicklerville, US
• Chunhong He · Boothwyn, US
• Taisheng Huang · Wilmington, US
• Song Mei · Wilmington, US
• Jun Pan · Media, US
• Xiaozhao Wang · Readington, US
• Yingda Ye · Wilmington, US

Key dates

• Filing date: Aug 25, 2016
• Grant date: Aug 21, 2018
• Expiry date: Aug 25, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.