Patent · US Active

MiRNA-489 in treatment of breast cancer

US10053696B2 · kind B2 · utility

3Cited by

0References

16Claims

0Family size

Assignee

UNIVERSITY OF SOUTH CAROLINA · US

Inventors

Hexin Chen · Columbia, US
Yogin PATEL · West Columbia, US
Nirav Shah · Vadodara, IN

Key dates

Filing date	Jan 20, 2017
Grant date	Aug 21, 2018
Priority date	—
Expiry date	Jan 20, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/178
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Breast cancer treatment methods and materials incorporating microRNA-489 are described. The methods and materials have been developed from identification of a double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis. The methods and materials may be particularly beneficial in treatment and diagnosis of HER2 positive breast cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.