Patent · US Active

Capsule array devices and methods of use

US10053723B2 · kind B2 · utility

112Cited by
193References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 28, 2017
Grant dateAug 21, 2018
Priority date
Expiry dateSep 28, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2535/122
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

This disclosure provides microwell capsule array devices. The microwell capsule array devices are generally capable of performing one or more sample preparation operations. Such sample preparation operations may be used as a prelude to one more or more analysis operations. For example, a device of this disclosure can achieve physical partitioning and discrete mixing of samples with unique molecular identifiers within a single unit in preparation for various analysis operations. The device may be useful in a variety of applications and most notably nucleic-acid-based sequencing, detection and quantification of gene expression and single-cell analysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.