Patent · US Active

Nuclear factor-erythroid 2 related factor 2 (NRF2) biosensors and modulators of NRF2

US10054583B2 · kind B2 · utility

2Cited by

0References

6Claims

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Assignee

Temple University-Of The Commonwealth System of Higher Education · US

Inventors

Oscar M. Perez-Leal · Philadelphia, US
Salim Merali · Queens, US
Carlos A. Barrero · Philadelphia, US

Key dates

Filing date	Oct 9, 2013
Grant date	Aug 21, 2018
Priority date	—
Expiry date	Oct 9, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compositions include nucleic acid sequences encoding the C-terminal fragment of fragment (Seg3) of Nuclear factor-erythroid 2 related factor 2 (Nrf2). These compositions provide a target for identification of novel therapeutics having the ability to modulate the translation of Nrf2. Methods of treating subjects are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.