Sulfated polygulonic acid polysaccharide or pharmaceutical salt thereof, preparation method therefor and use thereof

US10058566B2 · kind B2 · utility

Assignee

• SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

• Jian Ding · Shanghai, CN
• Jing Ai · Shanghai, CN
• Yi Chen · Shanghai, CN
• Xun Huang · Shanghai, CN

Key dates

• Filing date: Jul 2, 2014
• Grant date: Aug 28, 2018
• Expiry date: Nov 30, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08L5/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A polygulonic acid sulfate or pharmaceutically acceptable salt thereof, preparation method therefor and use thereof in the preparation of tumor growth and/or metastasis inhibitors are disclosed. The polygulonic acid sulfate or pharmaceutically acceptable salt thereof of the present invention can be used in the preparation of any one or more of tumor growth inhibitors, tumor metastasis inhibitors, angiogenesis inhibitors, heparanase inhibitors, C-Met enzyme inhibitors, microtubule polymerization inhibitors, actin-depolymerizing factor activity inhibitors and actin-aggregation inhibitors.