Microorganism for methionine production with enhanced methionine efflux
US10059970B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 1, 2014 |
| Grant date | Aug 28, 2018 |
| Priority date | — |
| Expiry date | Sep 1, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is related to a recombinant Escherichia coli (E. coli) strain optimised for the fermentative production of methionine and/or its derivatives, wherein in said recombinant strain, the methionine import is attenuated and the methionine efflux is enhanced. It is also related to a method for optimising the fermentative production of methionine or its derivatives comprising the steps of: a. culturing a recombinant microorganism wherein in said microorganism, the methionine import is attenuated and the methionine efflux is enhanced, in an appropriate culture medium comprising a fermentable source of carbon and a source of sulphur, and b. recovering methionine and/or its derivatives from the culture medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.