Biomarkers of autism spectrum disorder
US10060932B2 · kind B2 · utility
3Cited by
22References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 3, 2014 |
| Grant date | Aug 28, 2018 |
| Priority date | — |
| Expiry date | Jul 3, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16C20/70
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for identifying metabolic signatures in blood plasma which are unique to autism are described herein. Samples are analyzed using multiple chromatographic-mass spectrometry-based techniques to orthogonally measure a broad range of small molecular weight metabolites differentially produced in autistic patient samples versus non-autistic control samples. These individual metabolites or a panel of such metabolites serve as metabolic signatures of autism. Such metabolic signatures are used in diagnostic methods to accurately identify individuals with autism spectrum disorder (ASD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.