Patent · US Active

Multiple-layer immune barrier for donor cells

US10064976B2 · kind B2 · utility

2Cited by
2References
14Claims
0Family size

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Inventors

Key dates

Filing dateFeb 10, 2017
Grant dateSep 4, 2018
Priority date
Expiry dateFeb 10, 2037

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S623/915
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A system is provided, including a plurality of donor cells and a first alginate structure that encapsulates the plurality of donor cells. The first alginate structure has a guluronic acid concentration of between 64% and 74%. The system additionally includes a second alginate structure that surrounds the first alginate structure, the second alginate structure having a mannuronic acid concentration of between 52% and 60%. A selectively-permeable membrane is coupled at least in part to the second alginate structure. Other embodiments are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.