Apparatus and method for promoting angiogenesis in ischemic tissue
US10065018B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Sep 16, 2016 |
| Grant date | Sep 4, 2018 |
| Priority date | — |
| Expiry date | Oct 6, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/32
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A biologics delivery device and method of use for promoting angiogenesis in occluded vessels and ischemic tissue of a patient are provided, wherein the biologics delivery device includes a catheter having a proximal end, a distal region having a distal end, and a side wall defining a catheter lumen; an expandable member disposed in the distal region, the expandable member configured to support a subintimal space in an occluded blood vessel of a patient, and to transition between a collapsed state and an expanded state; and a hollow needle having a penetration tip deployable from inside the catheter lumen to outside the catheter lumen, and into tissue surrounding the occluded blood vessel, wherein the expandable member in the expanded state allows the flow of oxygenated blood to the occluded blood vessel. Methods of using the inventive biologics delivery device also are provided to deposit the biologic from a subintimal space to tissue surrounding the occluded blood vessel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.