Patent · US Active

Histone deacetylase inhibitors and compositions and methods of use thereof

US10065948B2 · kind B2 · utility

1Cited by
7References
51Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 1, 2015
Grant dateSep 4, 2018
Priority date
Expiry dateJun 1, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D403/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.