Amide derivatives of 1-oxa-4,9-diazaspiro undecane compounds having multimodal activity against pain
US10065971B2 · kind B2 · utility
0Cited by
3References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 2, 2015 |
| Grant date | Sep 4, 2018 |
| Priority date | — |
| Expiry date | Jun 2, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opiod receptor and more particularly to diazaspiro undecane compounds having this pharmacological activity, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain. wherein Y is n is 1 or 2; q is 1, 2, 3, 4, 5 or 6; X is a bond, —C(O)O—, —C(O)NR8—, —C(O)—, —O— or —C(R4R4′)—; R1 is C(O)R5 or S(O)2R5.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.