Nanoemulsion synthetic red blood cells having sequentially formed calcium phosphate coating and preparation method thereof
US10071111B1 · kind B1 · utility
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12Claims
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Key dates
| Filing date | Mar 29, 2017 |
| Grant date | Sep 11, 2018 |
| Priority date | — |
| Expiry date | Mar 29, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to nanoemulsion type synthetic red blood cells having a calcium phosphate coating of controllable thickness, and to a preparation method thereof. According to the present invention, Ca2+ and PO42− coating layers are uniformly and sequentially formed using a layer-by-layer (LBL) coating method while controlling the thicknesses of the coating layers. Thus, the oxygen capacity and oxygen release rate of the synthetic red blood cells can be controlled, and the synthetic red blood cells can be retrieved and reused.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.