Resorbable embolization spheres
US10071181B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 18, 2016 |
| Grant date | Sep 11, 2018 |
| Priority date | — |
| Expiry date | Apr 18, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/36
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Embolic materials, suspensions, kits and related methods useful for embolization are disclosed. An embolic material can comprise a resorbable microsphere including cross-linked gelatin as its primary ingredient and having a substantially spherical shape with a diameter of about 50 micrometers to about 1,500 micrometers, inclusive. The microsphere can optionally include one or both of a marker or an active agent. The microsphere can be cross-linked, such as with glutaraldehyde or formaldehyde, which can affect the microsphere's in vivo degradation profile and ability to withstand a sterilization process at certain temperatures. In an embodiment, the microspheres can resorb during an in vivo time period of between about 24 hours and about 15 weeks, inclusive. An embolization suspension can include a plurality of resorbable microspheres and a liquid carrier, and the suspension can be disposed in a syringe, vial or other applicator for administration to a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.