Antibodies that neutralize RSV, MPV and PVM and uses thereof
US10072071B2 · kind B2 · utility
1Cited by
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31Claims
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Assignee
Inventor
Key dates
| Filing date | Aug 10, 2016 |
| Grant date | Sep 11, 2018 |
| Priority date | — |
| Expiry date | Oct 12, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18522
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to antibodies, and antigen binding fragments thereof, that neutralize infection of both RSV, MPV and PVM. The invention also relates to nucleic acids that encode, immortalized B cells and cultured plasma cells that produce, and to polypeptides that bind to such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and polypeptides recognized by the antibodies of the invention in screening methods as well as in the diagnosis, treatment and prevention of RSV or MPV infection and RSV and MPV co-infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.