Patent · US Active

Pseudomonas aeruginosa PCRV binding single variable domain antibodies

US10072098B2 · kind B2 · utility

4Cited by

0References

25Claims

0Family size

Assignee

Ablynx N.V. · BE

Inventors

Evelyn De Tavernier · Deurle, BE
Ann Union · Aalter, BE
Bruno Dombrecht · Heusden, BE
Guy Hermans · Merelbeke, BE
Erika Morizzo · Wondelgem, BE

Key dates

Filing date	Mar 4, 2013
Grant date	Sep 11, 2018
Priority date	—
Expiry date	Mar 4, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Polypeptides are provided that are capable of significantly inhibiting and/or neutralizing P aeruginosa. The polypeptides comprise two or more immunoglobulin single variable domains that are directed against the PcrV protein of P. aeruginosa, wherein the “first” immunoglobulin single variable domain and the “second” immunoglobulin single variable domain have different paratopes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.