System and method for quantitative magnetic resonance (MR) analysis using T1 mapping
US10076264B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 31, 2016 |
| Grant date | Sep 18, 2018 |
| Priority date | — |
| Expiry date | May 31, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H30/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Example apparatus and methods concern determining whether a target material appears in a region experiencing nuclear magnetic resonance (NMR). One method acquires a baseline value for a magnetic resonance parameter (MRP) while the region is not exposed to a molecular imaging agent that affects the MRP and acquires a series of quantitative values for the MRP while the sample is influenced by a molecular imaging agent. Quantitative values may be acquired during a clinically relevant time period (e.g., 60 minutes) during which the change in the MRP (e.g., T1) caused by the molecular imaging agent is at least 90% of the peak change caused by the molecular imaging agent. The molecular imaging agent may be SBK2 and may produce a desired change in T1 for at least thirty minutes in glioblastoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.