Interactive dose gradient based optimization technique to control IMRT delivery complexity

US10076673B2 · kind B2 · utility

Assignee

• KONINIKLIJKE PHILIPS N.V. · NL

Inventors

• Vaitheeswaran RANGANATHAN · Bengaluru, IN
• Gipson JOE ANTO · Thodupuzha, IN
• Prashant Kumar · Bengaluru, IN
• Sivaramakrishnan Krishnaiyer Raman · Bengaluru, IN
• Deepak Uddhavrao Mahajan · Bengaluru, IN

Key dates

• Filing date: Apr 17, 2014
• Grant date: Sep 18, 2018
• Expiry date: Oct 7, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N2005/1074
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method for dose-gradient based optimization of an intensity modulated radiation therapy plan. First, an optimizer (6) performs a first optimization (40) of the plan to generate dose distributions corresponding to the plan. Next, the optimizer (6) generates a beam specific dose gradient map (42) for each beam of the plan. Then, new dose gradients are specified (44) for the plan. Last, the optimizer (6) performs a final optimization (46) using the new dose gradients. The final optimization is given the new dose gradients as soft constraints into an objective function. The optimizer (3) applies a limiting factor to the objective function such that a first dose gradient is limited by the optimizer only if the first dose gradient exceeds the new dose gradient for a specific beamlet.