Patent · US Active

Heteroaromatic compounds and their use as dopamine D1 ligands

US10077272B2 · kind B2 · utility

0Cited by
20References
19Claims
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Inventors

Key dates

Filing dateNov 27, 2017
Grant dateSep 18, 2018
Priority date
Expiry dateNov 27, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.