Antibodies against PD-1 and uses thereof
US10077305B2 · kind B2 · utility
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2References
11Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 9, 2014 |
| Grant date | Sep 18, 2018 |
| Priority date | — |
| Expiry date | Apr 30, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/70503
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides antibodies and antigen-binding fragments that specifically bind PD-1 (Programmed Death 1), thereby modulating immune responses in general, and those mediated by TcR and CD28, in particular. The disclosed compositions and methods may be used for example, in treating autoimmune diseases, inflammatory disorders, allergies, transplant rejection, cancer and other immune system disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.