Assays and enhancers of the human delta ENaC sodium channel
US10078087B2 · kind B2 · utility
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4References
31Claims
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Key dates
| Filing date | Jan 26, 2007 |
| Grant date | Sep 18, 2018 |
| Priority date | — |
| Expiry date | Nov 25, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/14
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to electrophysiological assays that measure sodium conductance activity of a delta human epithelial sodium channel (ENaC) in the presence and absence of delta hENaC enhancers. Also, the invention generally relates to assays for identifying compounds that enhance the activity of delta hENaC, especially in an oocyte expression system. These compounds have potential application in modulating (enhancing) salty taste perception.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.