Hot-melt extruded pharmaceutical dosage form

US10080721B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Lutz Barnscheid · Mönchengladbach, DE
• Eric Galia · Jülich, DE

Key dates

• Filing date: Jul 21, 2010
• Grant date: Sep 25, 2018
• Expiry date: Jul 19, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a hot-melt extruded pharmaceutical dosage form with controlled release of a pharmacologically active ingredient (A) embedded in a matrix comprising a polymer (C), the dosage form exhibiting a breaking strength of at least 300 N and having an oblong shape comprising a longitudinal direction of extension, a transversal direction of extension orthogonal to the longitudinal direction of extension, a front side, an opposite back side and a circumferential rim between said front and back side;wherein