Isoxazole derivatives as FXR agonists and methods of use thereof
US10080742B2 · kind B2 · utility
3Cited by
9References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 2017 |
| Grant date | Sep 25, 2018 |
| Priority date | — |
| Expiry date | Apr 26, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.