Patent · US Active

Efficient and scalable synthesis of 2-(1′h-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester and its structural analogs

US10081610B2 · kind B2 · utility

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25Claims

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Assignee

ARIAGEN, INC. · US

Inventors

Jiasheng Song · Madison, US
Suoming Zhang · Shanghai, CN
Guodong Li · Hornsby, AU
Luquing Yang · Shanghai, CN

Key dates

Filing date	Sep 10, 2015
Grant date	Sep 25, 2018
Priority date	—
Expiry date	Sep 10, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C67/47
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Methods of synthesizing 2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) and structural analogs thereof. The methods include condensation reactions or condensation and oxidation reactions to form the thiazoline or thiazole moiety of ITE or its structural analogs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.