Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-α]pyrazine-2-carboxamides as RSK inhibitors
US10081632B2 · kind B2 · utility
2Cited by
5References
17Claims
0Family size
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Key dates
| Filing date | Jul 31, 2017 |
| Grant date | Sep 25, 2018 |
| Priority date | — |
| Expiry date | Jul 31, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity: wherein R2, R4a, R4b, R11, R12, and n are defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.