Method for catalytic preparation of hydromorphone, hydrocodone, and other opiates
US10081636B2 · kind B2 · utility
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40Claims
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Key dates
| Filing date | Jul 7, 2017 |
| Grant date | Sep 25, 2018 |
| Priority date | — |
| Expiry date | Jul 7, 2037 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2531/822
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are provided for efficient preparation of hydromorphone or hydrocodone by redox isomerization of morphine or codeine allylic alcohols, respectively, using transition metal aminophosphine catalysts formed in situ.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.