Truncated HIV envelope proteins (ENV), methods and compositions related thereto

US10081658B2 · kind B2 · utility

Assignees

• Advanced BioScience Laboratories, Inc. · US
• The United States of America as represented by the Secretary of the Army · US
• The Henry M. Jackson Foundation for the Advancement of Military Medicines, Inc. · US

Inventors

• Vaniambadi Kalyanaraman · Germantown, US
• Stephen Whitney · Silver Spring, US
• Thomas C. VanCott · Brookeville, US
• Victoria Polonis · Silver Spring, US
• Carl R. Alving · Bethesda, US
• Gary R. Matyas · Olney, US
• Mangala Rao · Silver Spring, US
• Mary Marovich · Bethesda, US
• Francine McCutchan · Silver Spring, US
• Sodsai Tovanabutra · Gaithersburg, US
• Eric Sanders-Buell · Vienna, US

Key dates

• Filing date: Apr 25, 2012
• Grant date: Sep 25, 2018
• Expiry date: Jul 13, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16134
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.